FILE - This file publicity image provided by FX shows Charlie Sheen as Charlie Goodson and Selma Blair as Kate Wales in a scene from the new comedy "Anger Management." FX network says Thursday's debut of his sitcom, "Anger Management," was the most-watched series premiere in that network's history, drawing 5.5 million viewers. Then the audience for the evening's second episode grew to more than 5.7 million viewers, FX said Friday, June 29, 2012. (AP Photo/FX, Adam Rose)
FILE - This file publicity image provided by FX shows Charlie Sheen as Charlie Goodson and Selma Blair as Kate Wales in a scene from the new comedy "Anger Management." FX network says Thursday's debut of his sitcom, "Anger Management," was the most-watched series premiere in that network's history, drawing 5.5 million viewers. Then the audience for the evening's second episode grew to more than 5.7 million viewers, FX said Friday, June 29, 2012. (AP Photo/FX, Adam Rose)
NEW YORK (AP) ? Charlie Sheen can claim a winning reception back on weekly TV.
FX network says Thursday's debut of his sitcom, "Anger Management," was the most-watched series premiere in that network's history, drawing 5.5 million viewers. FX said Friday that the audience for the evening's second episode grew to more than 5.7 million viewers.
"Anger Management" marks Sheen's return to sitcoms after his tumultuous exit from his long-running CBS hit "Two and a Half Men" last season.
Dr. Douglas Wallace to receive Gruber Foundation 2012 Genetics PrizePublic release date: 29-Jun-2012 [ | E-mail | Share ]
Contact: Dana Mortensen mortensen@email.chop.edu 267-426-6067 Children's Hospital of Philadelphia
$500,000 award honors pioneering research by scientist at the Children's Hospital of Philadelphia
Douglas C. Wallace, Ph.D., director of the Center for Mitochondrial and Epigenomic Medicine at The Children's Hospital of Philadelphia, will receive the 2012 Genetics Prize of The Gruber Foundation. This prestigious international awarda $500,000 prizerecognizes Wallace's pioneering scientific investigations of the wide-ranging role of mitochondria in the development of disease and as markers of human evolution. Mitochondria are the tiny power plants within the cytoplasm of animal and plant cells.
Wallace will receive the award on November 9 at the annual meeting of the American Society of Human Genetics in San Francisco. The Gruber Foundation, now based at Yale University, announced the Genetics Prize on June 28. The Foundation's Genetics Prize annually honors leading scientists for groundbreaking contributions to genetics research.
Philip R. Johnson, MD, chief scientific officer at The Children's Hospital of Philadelphia, acknowledged Wallace's achievements, saying, "The Children's Hospital of Philadelphia Research Institute is privileged to number Douglas Wallace among our research leaders. His commitment to the field of mitochondrial genetics and his pioneering nature embody the mission of research at CHOP, and his research and leadership are shaping the way we approach therapies for genetic disorders previously considered beyond treatment."
"Douglas Wallace's contributions to our understanding of mitochondrial genetics have changed the way human and medical geneticists think about the role of mitochondria in human health and disease," said Dr. Elizabeth Blackburn, chair of the Selection Advisory Board to the Prize. Blackburn, who shared the 2009 Nobel Prize in Physiology or Medicine, also received the Gruber Genetics Prize in 2006.
Wallace, who came to The Children's Hospital of Philadelphia in 2010 to launch the Center for Mitochondrial and Epigenomic Medicine, first achieved prominence in the 1970s as the leader of a research team at Stanford University that defined the genetics of mitochondrial DNA. This DNA resides within each mitochondrion, as distinct from the more familiar nuclear DNA inside chromosomes. His group showed that human mitochondrial DNA is inherited exclusively from the mother.
This discovery, coupled with other findings, allowed the researchers to reconstruct ancient human migration patterns over hundreds of millennia, a major contribution that bridges genetics and anthropology. Wallace and colleagues also have linked mutations in mitochondrial DNA to a broad range of human diseases, including types of blindness, deafness, metabolic disorders such as diabetes, neuropsychiatric conditions, and age-related diseases such as heart disease and cancer.
The Center for Mitochondrial and Epigenomic Medicine at Children's Hospital researches mitochondrial dysfunction in many clinical problems, and also focuses on preclinical studies relevant to developing therapies for mitochondrial diseases, for which few effective clinical treatments currently exist.
Wallace holds the Michael and Charles Barnett Endowed Chair in Pediatric Mitochondrial Medicine at Children's Hospital and also is a professor of Pathology and Laboratory Medicine in the Perelman School of Medicine at the University of Pennsylvania. He is a member of the National Academy of Sciences, the nation's premier organization of leading researchers, as well as the Academy's Institute of Medicine, and is also a member of the American Academy of Arts and Sciences.
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About The Children's Hospital of Philadelphia: The Children's Hospital of Philadelphia was founded in 1855 as the nation's first pediatric hospital. Through its long-standing commitment to providing exceptional patient care, training new generations of pediatric healthcare professionals and pioneering major research initiatives, Children's Hospital has fostered many discoveries that have benefited children worldwide. Its pediatric research program is among the largest in the country, ranking third in National Institutes of Health funding. In addition, its unique family-centered care and public service programs have brought the 516-bed hospital recognition as a leading advocate for children and adolescents. For more information, visit http://www.chop.edu.
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Dr. Douglas Wallace to receive Gruber Foundation 2012 Genetics PrizePublic release date: 29-Jun-2012 [ | E-mail | Share ]
Contact: Dana Mortensen mortensen@email.chop.edu 267-426-6067 Children's Hospital of Philadelphia
$500,000 award honors pioneering research by scientist at the Children's Hospital of Philadelphia
Douglas C. Wallace, Ph.D., director of the Center for Mitochondrial and Epigenomic Medicine at The Children's Hospital of Philadelphia, will receive the 2012 Genetics Prize of The Gruber Foundation. This prestigious international awarda $500,000 prizerecognizes Wallace's pioneering scientific investigations of the wide-ranging role of mitochondria in the development of disease and as markers of human evolution. Mitochondria are the tiny power plants within the cytoplasm of animal and plant cells.
Wallace will receive the award on November 9 at the annual meeting of the American Society of Human Genetics in San Francisco. The Gruber Foundation, now based at Yale University, announced the Genetics Prize on June 28. The Foundation's Genetics Prize annually honors leading scientists for groundbreaking contributions to genetics research.
Philip R. Johnson, MD, chief scientific officer at The Children's Hospital of Philadelphia, acknowledged Wallace's achievements, saying, "The Children's Hospital of Philadelphia Research Institute is privileged to number Douglas Wallace among our research leaders. His commitment to the field of mitochondrial genetics and his pioneering nature embody the mission of research at CHOP, and his research and leadership are shaping the way we approach therapies for genetic disorders previously considered beyond treatment."
"Douglas Wallace's contributions to our understanding of mitochondrial genetics have changed the way human and medical geneticists think about the role of mitochondria in human health and disease," said Dr. Elizabeth Blackburn, chair of the Selection Advisory Board to the Prize. Blackburn, who shared the 2009 Nobel Prize in Physiology or Medicine, also received the Gruber Genetics Prize in 2006.
Wallace, who came to The Children's Hospital of Philadelphia in 2010 to launch the Center for Mitochondrial and Epigenomic Medicine, first achieved prominence in the 1970s as the leader of a research team at Stanford University that defined the genetics of mitochondrial DNA. This DNA resides within each mitochondrion, as distinct from the more familiar nuclear DNA inside chromosomes. His group showed that human mitochondrial DNA is inherited exclusively from the mother.
This discovery, coupled with other findings, allowed the researchers to reconstruct ancient human migration patterns over hundreds of millennia, a major contribution that bridges genetics and anthropology. Wallace and colleagues also have linked mutations in mitochondrial DNA to a broad range of human diseases, including types of blindness, deafness, metabolic disorders such as diabetes, neuropsychiatric conditions, and age-related diseases such as heart disease and cancer.
The Center for Mitochondrial and Epigenomic Medicine at Children's Hospital researches mitochondrial dysfunction in many clinical problems, and also focuses on preclinical studies relevant to developing therapies for mitochondrial diseases, for which few effective clinical treatments currently exist.
Wallace holds the Michael and Charles Barnett Endowed Chair in Pediatric Mitochondrial Medicine at Children's Hospital and also is a professor of Pathology and Laboratory Medicine in the Perelman School of Medicine at the University of Pennsylvania. He is a member of the National Academy of Sciences, the nation's premier organization of leading researchers, as well as the Academy's Institute of Medicine, and is also a member of the American Academy of Arts and Sciences.
###
About The Children's Hospital of Philadelphia: The Children's Hospital of Philadelphia was founded in 1855 as the nation's first pediatric hospital. Through its long-standing commitment to providing exceptional patient care, training new generations of pediatric healthcare professionals and pioneering major research initiatives, Children's Hospital has fostered many discoveries that have benefited children worldwide. Its pediatric research program is among the largest in the country, ranking third in National Institutes of Health funding. In addition, its unique family-centered care and public service programs have brought the 516-bed hospital recognition as a leading advocate for children and adolescents. For more information, visit http://www.chop.edu.
[ | E-mail | Share ]
?
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
SACRAMENTO, CA ? June 28, 2012 ? (RealEstateRama) ? Attorney General Kamala D. Harris today announced the passage of two central elements of the California Homeowner Bill of Rights through a special two-house conference committee. The 4 to 1 vote sends the bills to an expected vote next week in both the Assembly and Senate.
The two bills approved by the conference committee are the Foreclosure Reduction Act, which restricts the process of ?dual-tracked? foreclosures and the Due Process Rights Act, which guarantees a reliable contact for struggling homeowners to discuss their loan with and which for the first time imposes civil penalties on the practice of fraudulently signing foreclosure documents without verifying their accuracy, a practice commonly known as ?robo-signing.? The proposed legislation also includes meaningful enforcement for borrowers whose rights are violated.
The full Homeowner Bill of Rights includes additional provisions to reduce blight, ensure appropriate law enforcement response to mortgage fraud and crime, and protect tenants. The bills containing these protections are also advancing through the Legislature.
?I am gratified by this vote, which represents one more step toward our goal of achieving a Homeowner Bill of Rights for California,? said Attorney General Harris. ?The mortgage and foreclosure crisis in our state demands urgent efforts to help Californians keep their homes. The legislature will now have the opportunity to cast a vote on behalf of California?s struggling homeowners.?
The California Homeowner Bill of Rights was introduced February 29, 2012 at a press conference featuring Assembly Speaker John A. Perez and Senate President pro Tem Darrell Steinberg and bill authors from the Assembly and Senate. The goal of the Homeowner Bill of Rights is to take many of the mortgage reforms extracted from banks in a national mortgage settlement and write them into California law so they could apply to all mortgage-holders in the state.
?The mortgage and foreclosure abuse in California ends here,? said Noreen Evans (D-Santa Rosa), co-chair of the Joint Conference Committee. ?This committee has passed historic legislation that codifies the protections eligible homeowners deserve, while helping to stabilize the foreclosure crisis that has thwarted California?s economic recovery. The Legislature has studied, listened and engaged Californians and industry to find a solution that is fair and effective to mitigate this crisis. I look forward to the full support of the Legislature and Governor in implementing this package.?
?This bill is the result of a long and difficult process in which we received input from all interested parties; including homeowners and the banks and found that foreclosures benefit no one,? said Assemblymember Mike Eng (D-Alhambra). ?We ended such dubious practices as having a bank foreclose while a homeowner is in the process of modifying a loan and cut through confusion by making sure that there is a ?single point of contact? with mortgage servicers. With half a million California homes at risk of foreclosure, this action was urgently needed.?
The California Homeowner Bill of Rights extends Attorney General Harris? response to the state?s foreclosure and mortgage crisis. Attorney General Harris created a Mortgage Fraud Strike Force in March, 2011 to investigate and prosecute misconduct related to mortgages and foreclosures. In February 2012 Attorney General Harris extracted a commitment from the nation?s five largest banks of an estimated $18 billion for California borrowers.
More details about the California Homeowner Bill of Rights are found on the attached fact sheet. To learn more about how the bills impact California homeowners, review the slideshow at: www.oag.ca.gov.
The most remarkable thing about Google's Nexus 7 tablet can't be found on its spec sheet. It won't show up in any benchmark, and it has nothing to do with that zippy new operating system. If you want to know the true significance of the Nexus 7, all you need to look at is the price tag. More »
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Public release date: 29-Jun-2012
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