Friday, February 8, 2013

Tornado Pepper Spray Self-Defense System ? Product Review ...

Related eBooks

Self-defense products that can do more than one thing at a time have my admiration for the simple reason that they can protect you in many ways. The Tornado pepper spray system is a great example of what I?m talking about. Read on to learn more.

Source:Tornado Pepper Spray Self-Defense System ? Product Review

Related Reading:

Complete Krav Maga: The Ultimate Guide to Over 230 Self-Defense and Combative TechniquesComplete Krav Maga: The Ultimate Guide to Over 230 Self-Defense and Combative TechniquesDeveloped for the Israel military forces and battle tested in real-life combat, Krav Maga has gained an international reputation as an easy-to-learn yet highly effective art of self-defense. Clearly written and extensively illustrated, Complete Krav Maga details every aspect of the system including dozens of hand-to-hand combat moves, over 20 weapons defense techniques and a complete physical conditioning workout program.

All the moves are described in depth from beginning Yellow Belt to advanced Black Belt, yet they are easy to learn because one of Krav Maga's strengths is its simplicity. Based on the principle that it is best to move from defense to attack as quickly as possible, Complete Krav Maga offers fast-escape maneuvers from attacks and holds. It then follows them up with specific counterattacks, including punches, kicks and throws.

The authors show how anyone (big or small, man or woman) can practice self defense by using Krav Maga to protect weak spots, exploit an assailant's vulnerabilities and turn the attacker s force against him. Complete Krav Maga teaches the reader how to get in shape, gain confidence and feel safer and more secure every day.

The SAS Self-Defense HandbookThe SAS Self-Defense Handbook

Essential self-defense training from the elite British SAS.

Barry Davies is one of the most widely respected experts on the techniques and training of the elite British Special Air Service (SAS). In The SAS Self-Defense Handbook, Davies reveals the self-defense techniques of the SAS. The handbook is fully illustrated with nearly 130 photographs and illustrations that explain how to properly use your body and use everyday objects such as desktop items and cigarette lighters to protect yourself. Learn how to avoid physical attacks from humans and animals, and handle those confrontations that cannot be avoided. 83 color and 39 black-and-white illustrations

Tags: self defense

Source: http://www.jackiesbazaar.com/womensinterests/self-defense/tornado-pepper-spray-self-defense-system-product-review

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Thursday, February 7, 2013

For drug makers, new 3-D control opens wealth of options

Feb. 7, 2013 ? A team of scientists anchored at Yale University has demonstrated a new, highly versatile approach for quickly assembling drug-like compounds, establishing a broad new route to drug discovery and medical treatment. They report their results in the journal Science on Feb 8.

Drug molecules interact with their targets, such as proteins or enzymes, by attaching to them in a way that neutralizes the target's undesirable effects in the body. This is sometimes called the "lock-and-key" method. The new approach offers scientists far greater control over the three-dimensional structure of a key class of molecular compounds, making it easier to fashion drug molecules that fit their targets in the right way.

"Now we've got a lot more control over the shape and orientation of this class of drug compounds, and this essentially gives us greater flexibility in creating effective drugs," said Jonathan Ellman, the Yale chemist who led the experiment.

The research reported in Science revolves around piperidines, a class of organic compounds widely used in pharmaceuticals, including the familiar drugs quinine, morphine, oxycodone, Plavix, Cialis, and Aricept. Piperidines are core structures, or scaffolds, upon which molecular fragments -- parts of the drug molecule -- can be displayed for binding to a drug's targets. The scientists have shown a way to generate different piperidine derivatives by varying acid strength.

"Our research allows us to make new piperidines easily," Ellman said. "The approach has biomedical relevance because the scaffold upon which the fragments are displayed is present in many of the most important drugs."

The research is being published without patent constraints and could be used by drug developers immediately, said Ellman, who is the Eugene Higgins Professor of Chemistry and professor of pharmacology. "I believe that this is the most effective approach for rapidly translating this work into new drugs," he said.

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The above story is reprinted from materials provided by Yale University, via EurekAlert!, a service of AAAS.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. S. Duttwyler, S. Chen, M. K. Takase, K. B. Wiberg, R. G. Bergman, J. A. Ellman. Proton Donor Acidity Controls Selectivity in Nonaromatic Nitrogen Heterocycle Synthesis. Science, 2013; 339 (6120): 678 DOI: 10.1126/science.1230704

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/matter_energy/biochemistry/~3/sru0kxUANAQ/130207141500.htm

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Micex IPO is an FX plan | beyondbrics - Blogs - Financial Times

By Ben Aris of bne

The management of Russia?s MICEX exchange arrived in London on Tuesday on a roadshow ahead of its IPO on Feburary 15. What they are selling is not just a stock exchange but a diversified business that is in many ways unique.

Widely seen as Russia?s leading stock exchange, MICEX is actually a unusually diversified business for an exchange, which means it has managed to earn steadily increasing profits that have been largely unaffected by the 2008 crisis, let alone the notorious volatility that plagues portfolio investors into Russian stocks.

Trading stocks and bonds made up only 34 per cent of MICEX?s operating income in the first nine months of 2012. The biggest single business on the exchange is foreign currency trading (FX) that accounts for 80 per cent of the aggregated trading volumes by value and, at just under a third, was the single biggest contributor to the operating income in same period.

It?s all in the name: MICEX stands for ?Moscow Interbank Currency Exchange?. The exchange was set up in 1992 as the money market platform for the banking sector and also for Central Bank of Russia (CBR) interventions on the currency market, used to control the exchange rate and provide support to the banking sector in times of crisis. Neither of these jobs are typical for an exchange and 20 years later its FX business still provides MICEX with a steady stream of income.

It only took on trading stocks in the second half of the 1990s and came into its own when the government ruled domestic Gazprom shares could only be traded on MICEX after it removed the so-called ring fence ? special rules that prevented foreigners buying locally listed shares in what at the time was Russia?s most valuable company.

In all the exchange trades five asset classes: in addition to stocks, bonds and currency it is also a platform for repo deals with fixed income instruments and also the burgeoning derivatives business.

And as well as handling issuance and trading, the exchange also unusually offers all the post-trade services of settlement, clearing and depository services as a single unified operation ? more steady revenues for the exchange irrespective of what else is happening in the country, which together make up 16 per cent of its total income.

Source: Micex

The advantage of having such a diversified business is the exchange?s income has risen pretty consistently over the last six years, despite the huge swings on its on trading floor, even during the worst of the 2008 meltdown, when the value of stocks traded on the exchange plummeted by about 75 per cent.

?MICEX keeps making money no matter what is happening on the exchange itself,? says one banker close to the business who didn?t want to be named. ?When share prices tank then derivatives spike. And the volumes of FX trading continue to grow no matter what else is going on in the country.?

Source: Micex

FX trading remains the exchange?s cash cow with volumes rising by a consolidated annual rate of growth of 24 per cent since 2009 to top in Rb295.5tn in 2012. And currency-trading volumes will only increase once restrictions on foreign investors buying bonds directly on the MICEX floor from their trading desks around the world are removed this month.

However, the fast growing business line is derivatives trading. Following the 1998 financial crisis the Central Bank ruled that derivatives were regulated by the same rules as casinos, as Russian banks attempted to wiggle out of some $40bn worth of forward contracts obligations signed with foreign investors to protect themselves from the very devaluation that actually happened.

Things have got better since then. A new law on investment was passed in 2002 that created the foundation of a real derivatives market and another covering futures trading was introduced in 2006. (All the casinos in Moscow have also since been closed and banished to remote regions in Russia?s interior.)

The derivatives business is booming. Because of a lack of domestic institutional investors, investors in Russian stocks have become increasingly keen to hedge against perennial volatility and part of the goal of merging MICEX with the RTS in 2012 was to further deepen the derivatives business, which now makes 18 per cent of the exchange?s income.

The exchange still quotes both the RTS and MICEX indices, which are now identical in terms of the basket of stocks and their weighting, except the RTS is denominated in dollars and used as a basis of hedging while the MICEX index is denominated in rubles. Last year, 43 per cent of all the derivate contracts written were against the RTS index value and worth a total of $3.8bn, making this derivative amongst the top six biggest derivative products in the world.

All in all MICEX reported revenues of Rb15.9bn ($530m) for the first nine months of 2012, a 36.7 per cent increase on the same period a year earlier, with net profits up by just under a quarter to Rb6.4bn ($213m). Going forward the exchange is travelling through Europe, America and the Russian regions (as this will be a Russian IPO on a Russian exchange after all) telling investors that the future looks even brighter.

The Kremlin is pushing to create an international financial centre in Moscow, but the ultimate goal is to win back Russia?s equity business from London, the preferred destination for most of Russia?s biggest IPOs.

Russian companies already account for 18 per cent of the London Stock Exchange?s total capitalization, according to President Vladimir Putin, but the president said last month that from this year he wants all the IPOs planned as part of the privatization drive to be held on the Moscow, not London, exchange. A few days later Andrei Kostin, CEO of VTB Bank, dutifully announced that VTB would sell its next tranche of a reported 10 per cent on MICEX, not the LSE. More will follow.

It will take a long time before MICEX can seriously threaten the LSE appeal for big Russian companies wanting to float. But the listing of MICEX and the new drive to promote domestic listings is another step along the road to creating a fully-fledged Russian capital market that can serve both pensioners and Russian companies looking to raise capital. It should also provide MICEX?S shareholders some nice and steady dividend payments in the process.

Related reading:
Putin: time to get serious about the stock market and privatisation, beyondbrics
Moscow bourse: no place like home, beyondbrics
Investors rush for Sberbank bond, beyondbrics
Moscow exchange presses ahead with IPO, FT

Source: http://blogs.ft.com/beyond-brics/2013/02/05/micex-ipo-is-an-fx-plan/

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Wednesday, February 6, 2013

Monopoly to get new lineup of tokens

FILE - This product image provided by Hasbro, shows the board game Monopoly. The end is near for the shoe, wheelbarrow or iron in the classic Monopoly game as fans vote Tuesday, Feb. 5, 2013 in the final hours of a contest to determine which token to eliminate and which piece to replace it with. (AP Photo/Hasbro, File)

FILE - This product image provided by Hasbro, shows the board game Monopoly. The end is near for the shoe, wheelbarrow or iron in the classic Monopoly game as fans vote Tuesday, Feb. 5, 2013 in the final hours of a contest to determine which token to eliminate and which piece to replace it with. (AP Photo/Hasbro, File)

(AP) ? The classic Monopoly game is set for its most significant change in decades after fans of the game designed nearly 80 years ago voted to add a new token to replace the shoe, wheelbarrow or iron after they received the least support in an online contest.

Toy maker Hasbro Inc. is scheduled to announce the new token lineup Wednesday morning, hours after fans cast their final ballots to determine which of the five proposed pieces to add and which of the existing tokens to eject.

The tokens identify the players and have changed quite a lot since Parker Brothers bought the game from its original designer in 1935.

The voting closed just before midnight Tuesday. Rhode Island-based Hasbro says the wheelbarrow, shoe and iron were neck and neck for elimination through the Save Your Token Campaign. The new addition will be a robot, diamond ring, cat, helicopter or guitar.

Fans from more than 120 countries have voted.

The online contest to change the tokens was sparked by chatter on Facebook, where Monopoly has more than 10 million fans. The initiative was intended to ensure that a game created nearly eight decades ago remains relevant and engaging to fans today.

Monopoly's iconic tokens originated when the niece of game creator Charles Darrow suggested using charms from her charm bracelet for tokens. The real-estate trading game is based on the streets of Atlantic City, N.J., and has sold more than 275 million games worldwide.

The current eight tokens are an iron, racecar, Scottie dog, a shoe, thimble, top hat, wheelbarrow and battleship. Most of the pieces were introduced with the first Parker Brothers iteration of the game in 1935, and the Scottie dog and wheelbarrow were added in the early 1950s.

Versions of Monopoly with the new token will come out later this year.

___

Monopoly: https://www.hasbro.com/monopoly

___

Rodrique Ngowi can be reached at www.twitter.com/ngowi

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/3d281c11a96b4ad082fe88aa0db04305/Article_2013-02-06-Monopoly-New%20Tokens/id-8ea5a37f1dad4bf9a811666accc4ffeb

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Routes towards defect-free graphene

Monday, February 4, 2013

A new way of growing graphene without the defects that weaken it and prevent electrons from flowing freely within it could open the way to large-scale manufacturing of graphene-based devices with applications in fields such as electronics, energy, and healthcare.

A team led by Oxford University scientists has overcome a key problem of growing graphene ? a one atom-thick layer of carbon ? when using an established technique called chemical vapour deposition, that the tiny flakes of graphene form with random orientations, leaving defects or 'seams' between flakes that grow together.

The discovery, reported in a paper to be published in ACS Nano, reveals how these graphene flakes, known as 'domains', can be lined up by manipulating the alignment of carbon atoms on a relatively cheap copper foil ? the atomic structure of the copper surface acts as a 'guide' that controls the orientation of the carbon atoms growing on top of them.

A combination of control of this copper guide and the pressure applied during growth makes it possible to control the thickness of these domains, the geometry of their edges and the grain boundaries where they meet ? 'seams' that act as obstacles to the smooth progress of electrons necessary to create efficient graphene-based electrical and electronic devices.

'Current methods of growing flakes of graphene often suffer from graphene domains not lining up,' said Professor Nicole Grobert of Oxford University's Department of Materials who led the work. 'Our discovery shows that it is possible to produce large sheets of graphene where these flakes, called 'domains', are well-aligned, which will create a neater, stronger, and more 'electron-friendly' material.'

In principle the size of the sheet of graphene that can be created is only limited by the size of the copper base sheet.

The Oxford-led team, which includes researchers from Forschungszentrum Juelich Germany, the University of Ioannina Greece, and Renishaw plc, has shown that it is also possible using the new technique to selectively grow bilayer domains of graphene ? a double layer of closely packed carbon atoms ? which are of particular interest for their unusual electrical properties.

'People have used copper as a base material before, but this is the first time anyone has shown that the many different types of copper surfaces can indeed strongly control the structure of graphene,' said Professor Grobert. 'It's an important step towards finding a way of manufacturing graphene in a controlled fashion at an industrial scale, something that is essential if we are to bridge the gap between fundamental research and building useful graphene-based technologies.'

###

University of Oxford: http://www.ox.ac.uk/

Thanks to University of Oxford for this article.

This press release was posted to serve as a topic for discussion. Please comment below. We try our best to only post press releases that are associated with peer reviewed scientific literature. Critical discussions of the research are appreciated. If you need help finding a link to the original article, please contact us on twitter or via e-mail.

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Source: http://www.labspaces.net/126595/Routes_towards_defect_free_graphene

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Tuesday, February 5, 2013

Old Game On Computer in The AnswerBank: Gaming

oh it must have been a good 10 years ago. there was this game where you had an egyptian town and you could mine gold, some people had to shoot dear to support the food level. I think you just basically had to build a working sustainable village.

for the life of me i cant find it anywhere and i would love to play it again as i remember it being quite addictive. anyone know the name or even if its possible to buy it still?

Source: http://www.theanswerbank.co.uk/Gaming/Question1213697.html

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Catholic hospital takes surprise stance in lawsuit

DENVER (AP) ? It was a startling assertion that seemed an about-face from church doctrine: A Catholic hospital arguing in a Colorado court that twin fetuses that died in its care were not, under state law, human beings.

When the two-year-old court filing surfaced last month, it triggered an avalanche of criticism ? because the legal argument seemed to plainly clash with the church's centuries-old stance that life begins at conception.

But it is also now fueling an already raging debate in Colorado and beyond about whether fetuses should have legal rights and, if so, what kind.

On Monday, the hospital and the state's bishops released a statement acknowledging it was "morally wrong" to make the legal argument.

News of the wrongful death lawsuit came as Colorado lawmakers weigh how far they should go in penalizing acts that harm a fetus, and some worry that the case could diminish the Catholic Church's credibility in advocating more rights for the unborn.

Miguel De La Torre, a professor at the Iliff School of Theology in Denver, noted that the church often argues for laws recognizing a fetus as a human being.

"If that legislation was to come up again, how could the Catholic Church argue we should protect the rights of a fetus?" he said.

Indeed, last week Colorado's bishops met with executives at Catholic Healthcare Initiatives, a branch of the church that operates the hospital at the center of the case, to review how the lawsuit was handled. The two released separate statements Monday saying CHI executives had been unaware of the legal arguments and pledging to "work for comprehensive change in Colorado's law, so that the unborn may enjoy the same legal protections as other persons."

Spurred on by advancing medical technology that makes fetuses more viable and more visible, states have been expanding some rights to fetuses, sometimes in conjunction with anti-abortion groups and the Catholic Church.

State laws vary widely. It's difficult to quantify how many states allow wrongful death lawsuits on behalf of unborn children because each state has different case law and judicial interpretation. A report from the anti-abortion Americans United for Life estimates that 38 permit such lawsuits.

According to The Guttmacher Institute, which tracks reproductive health issues, 37 states allow some form of prosecution for killing a fetus. A federal law also makes it a crime to harm a fetus while committing other federal crimes.

The debate over such measures has been especially heated in Colorado, which has long battled over the legal status of unborn children. For example, Colorado has been ground zero for the "personhood" movement, which pushes laws that give fertilized eggs all the legal rights of human beings. Opponents warn that such laws would outlaw all forms of abortion and some types of birth control. Voters here so far have overwhelmingly rejected such proposals.

In 1986, a federal court ruled that fetuses are indeed people for purposes of wrongful death lawsuits in Colorado, but state courts have offered conflicting views. This latest case further calls the matter into question.

The case centers on St. Thomas More Medical Center in Canon City, a few hours south of Denver, and a wrongful death lawsuit filed by a husband who lost his pregnant wife.

Lori Stodghill was 28 weeks into her pregnancy when, on New Year's Day 2006, she began vomiting and feeling short of breath, according to court papers. Her husband, Jeremy, took her to the emergency room of St. Thomas More, where Stodghill collapsed and went into cardiac arrest.

Doctors and nurses tried to revive her, but she was declared dead from a pulmonary embolism. No one tried to remove the fetuses via an emergency cesarean section, and they perished, too, court papers said.

Jeremy Stodghill sued the hospital, some doctors and Catholic Healthcare Initiatives, which owns the company that operates Thomas More. Attorneys for CHI in 2010 filed court papers asking a judge to dismiss the case because the plaintiffs couldn't prove negligent care killed Lori Stodghill and her fetuses. They also argued that "under Colorado law, a fetus is not a 'person,' and Plaintiff's claims for wrongful death must therefore be dismissed."

The trial judge agreed, finding that previous state cases required a fetus to be "born alive" to have a legal claim. An appellate court upheld the dismissal on other grounds. Stodghill's attorneys are now asking the state Supreme Court to hear the case.

The arguments were first reported on Jan. 23 by The Colorado Independent and Westword and set off a firestorm because of Catholic health groups' past stances on such issues. The trade group representing Catholic Hospitals opposed a provision of the federal health care law mandating that birth control be covered by insurance.

In their Monday statement, Denver Archbishop Samuel J. Aquila, Colorado Springs Bishop Michael Sheridan and Pueblo Bishop Fernando Isern said: "Catholic healthcare institutions are, and should, be held to the high standard of Jesus Christ himself."

They and CHI pledged not to argue against fetal personhood further in the case. They also said they and CHI sympathize with the Stodghill family.

Attorney Timms Fowler, who wrote a brief on behalf of the Colorado Trial Lawyers Association in the case, doesn't believe that allowing lawsuits over wrongfully killed fetuses leads to giving them the same rights as human beings. He said there is a difference between "the duty owed by a stranger to the mother and the unborn child" and the mother's own decisions about the fetus' future.

"To die by the wrongful conduct of a stranger, you don't have to be a walking, talking, full person," Timms said, stressing he was speaking for himself and not the association.

Last Monday, no church representatives testified as a state legislative committee considered a proposal to make it a crime to kill a fetus. Republican Rep. Janak Joshi said his measure was not meant to wade into abortion politics but rather enable prosecutors to file additional charges in cases like the Aurora movie theater shooting. One victim was so severely wounded during the July massacre that she miscarried, but prosecutors could not file murder charges on her unborn child's behalf.

Witness Heather Surovik told the committee about how a drunken driver injured her last year and killed her 8 1/2-month-old unborn son, Brady. At the hospital, the emergency staff removed him from her body and dressed his corpse in infant clothes. Prosecutors could not file vehicular manslaughter charges because Brady was not legally a person.

Democrats and an attorney for Planned Parenthood argued that Joshi's measure, as written, could enshrine legal rights for fetuses in state law and lead to an abortion ban. The committee voted it down, but Democrats later unveiled their own bill that would make it a crime to kill a fetus during a criminal act committed against a pregnant woman. That measure specifically states that the intent is to neither outlaw abortions nor give unborn children additional rights.

A hearing on that proposal is scheduled later this month.

Source: http://news.yahoo.com/catholic-hospital-takes-surprise-stance-lawsuit-190735855.html

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